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帕博利珠单抗致免疫性心肌炎1例报告及文献回顾分析 被引量:2

A case report and literature review of immune myocarditis induced by pembrolizumab
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摘要 1例老年女性黑色素瘤患者接受帕博利珠单抗200 mg治疗,21 d后发生免疫性心肌炎伴横纹肌溶解,考虑与帕博利珠单抗治疗有关。经给予糖皮质激素冲击治疗和对症支持治疗,患者病情逐渐好转并出院。 An elderly female melanoma patient who received 200 mg of pembrolizumab developed immune myocarditis with rhabdomyolysis 21 days later,which was considered to be related to pembrolizumab treatment.The patient was given glucocorticoid pulse therapy and symptomatic treatment,her condition was gradually improved after treatment and was finally discharged from the hospital.
作者 李娟 贾婉 邱央 奚文崎 LI Juan;JIA Wan;QIU Yang;XI Wenqi(Department of Pharmacy,Ruijin Hospital,Shanghai Jiao Tong University School of Medicine,Shanghai 200025,China;Department of Pharmacy,Wuxi Branch of Ruijin Hospital,Shanghai Jiao Tong University School of Medicine,Wuxi 214000,China;Department of Pharmacy,Guhua Hospital of Fengxian District,Shanghai 201499,China;Department of Oncology,Ruijin Hospital,Shanghai Jiao Tong University School of Medicine,Shanghai 200025,China)
出处 《上海医药》 CAS 2022年第17期11-15,共5页 Shanghai Medical & Pharmaceutical Journal
关键词 帕博利珠单抗 免疫性心肌炎 免疫检查点抑制剂 pembrolizumab immune myocarditis immune checkpoint inhibitors
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