高强度间歇训练对慢性心力衰竭患者的疗效观察

The efficacy of high intensity interval training on patients with chronic heart failure

目的:探讨高强度间歇训练(HIIT)在慢性心力衰竭(CHF)患者中的应用效果。方法:将96例CHF患者随机分为对照组(n=48)和观察组(n=48)。对照组给予中等强度连续运动训练(MICT),观察组予以HIIT,连续干预12周。对比两组心肌损伤指标、心功能和生活质量。结果:干预12周后,观察组N末端脑钠肽前体(NT-proBNP)、高敏心肌肌钙蛋白(hs-cTn)、肌酸激酶同功酶(CK-MB)、左室收缩末期内径(LVESD)、左室舒张末期内径(LVEDD)低于对照组,左室射血分数(LVEF)、心理功能、躯体功能、社会功能与物质状态评分高于对照组(均P<0.05)。结论:HIIT能够减轻CHF患者心肌损伤,改善心功能,提高生活质量。

Objective:To investigate the effect of high intensity interval training(HIIT)in patients with chronic heart failure(CHF).Methods:Ninety-six patients with CHF were randomly divided into a control group(n=48)and an observation group(n=48).The control group was given moderate intensity continuous exercise training(MICT)and the observation group was given HIIT,and their intervention was lasted for continuous 12 weeks.The myocardial injury index,cardiac function and quality of life were compared between the two groups.Results:After 12 weeks of intervention,the levels of N-terminal brain natriuretic peptide precursor(NT-proBNP),high-sensitivity cardiac troponin(hs-cTn),creatine kinase isoenzyme(CK-MB),left ventricular end-systolic diameter(LVESD)and left ventricular end-diastolic diameter(LVEDD)were lower in the observation group than the control group,and the left ventricular ejection fraction(LVEF)and the scores of psychological function,physical function,social function and material status were higher in the observation group than the control group(all P<0.05).Conclusion:HIIT can reduce myocardial injury and improve cardiac function and quality of life in CHF patients.