宫腔镜子宫内膜息肉切术异丙酚复合芬太尼静脉麻醉对患者生命体征及术后苏醒时间的影响

Effects of propofol combined with fentanyl for intravenous anesthesia during hysteroscopic endometrial polypectomy of patients on their vital signs and postoperative recovery time

目的:研究宫腔镜子宫内膜息肉切术异丙酚复合芬太尼静脉麻醉对患者生命体征及术后苏醒时间的影响。方法:选取2019年9月-2020年9月本院行宫腔镜子宫内膜息肉切除术的患者78例,数字表法随机分为联合组和对照组,均接受异丙酚静脉麻醉,联合组复合芬太尼静脉麻醉,比较两组患者苏醒时间、麻醉起效时间、定向力恢复时间和不同时间生命体征[心率(HR)、平均动脉血压(MAP)、脉搏血氧饱和度(SPO_(2))],疼痛数字评价量表(NRS)评分术后疼痛情况,记录两组麻醉后不良反应。结果:联合组麻醉起效时间(0.63±0.12 min)、苏醒时间(3.83±1.62 min)和定向力恢复时间(6.90±3.85 min)均低于对照组(0.87±0.21 min、5.75±1.91 min、9.03±2.97 min),术中HR、MAP、SPO_(2)均高于对照组,苏醒后30min、60min NRS评分(6.33±1.04分、3.90±0.84分)均低于对照组(6.81±0.95分、4.35±0.97分)(均P<0.05),不良反应发生率(7.7%)与对照组(2.6%)无差异(P>0.05)。结论:宫腔镜子宫内膜息肉切除术使用异丙酚复合芬太尼静脉麻醉,起效快、有效缩短患者苏醒时间和定向力恢复时间,术中生命体征平稳,术后镇痛效果好。

Objective:To study the effects of propofol combined with fentanyl for intravenous anesthesia during hysteroscopic endometrial polypectomy of patients on their vital signs and postoperative recovery time.Methods:A total of 78 patients who wanted hysteroscopic endometrial polypectomy were enrolled in this study between September 2019 and September 2020.According to random number table method,these patients were divided into two groups.The patients in the observation group were given propofol combined with fentanyl for intravenous anesthesia,and the patients in the control group were given propofol alone for intravenous anesthesia.The recovery time,the anesthesia onset time,the orientation recovery time,the values of vital signs,such as heart rate(HR),mean arterial blood pressure(MAP),and pulse oxygen saturation(SPO_(2)),and the score of postoperative pain by Numerical Rating Scale(NRS)of the patients were compared between the two groups.And the adverse reactions situation of the patients in both groups after anesthesia were recorded.Results:The anesthesia onset time(0.63±0.12 min),the recovery time(3.83±1.62 min),and the orientation recovery time(6.90±3.85 min)of the patients in the observation group were significantly lower than those(0.87±0.21 min,5.75±1.91 min,and 9.03±2.97 min)of the patients in the control group.The values of HR,MAP,and SPO_(2) of the patients in the observation group during operation were significantly higher than those of the patients in the control group.The score of postoperative pain by NRS of the patients in the observation group in postoperative 30 min and 60 min were 6.33±1.04 points and 3.90±0.84 points,which were all significantly lower than those(6.81±0.95 points and 4.35±0.97 points)of the patients in the control group(all P<0.05).The incidence of adverse reaction of the patients in the observation group was 7.7%,which had no significant different from that(2.6%)of the patients in the control group(P>0.05).Conclusion:The application of propofol combined with fentanyl for intravenous anesthesia during hysteroscopic endometrial polypectomy of the patients takes anesthesia effect rapidly,which can effectively shortens the recovery time and the orientation recovery time,with stable intraoperative vital signs and good postoperative analgesia effect.