体素不相干运动成像技术评估胎儿生长受限胎盘血流灌注

Evaluation of placental blood perfusion of the pregnant women with fetal growth restriction by voxel incoherent motion imaging

目的:探讨利用体素不相干运动成像(IVIM)技术评估胎儿生长受限(FGR)胎盘血流灌注情况。方法:选择本院2019年1月20日-2020年2月1日FGR孕妇31例为病例组,年龄及孕周相匹配的胎儿发育正常孕妇31例为对照组,均行多b值DWI成像,并使用IVIM模型测量慢扩散系数D、快扩散系数D*及扩散系数f。结果:胎盘伪弥散系数D*及灌注分数f值病例组均低于对照组(20.37±6.34 mm^(2)/s比31.75±7.54 mm^(2)/s,P=0.006)(32.30%±4.17%比23.66%±3.87%,P=0.001);胎盘扩散系数D(1.68±0.26mm^(2)/s)与对照组(1.61±0.22 mm^(2)/s)无差异(P=0.64)。结论:IVIM技术可用来观察FGR孕妇胎盘血流灌注情况,为早期辅助诊断FGR提供帮助。

Objective:To investigate the evaluation of placental blood perfusion of the pregnant women with fetal growth restriction(FGR)by voxel incoherent motion imaging(IVIM).Methods:31 pregnant women with FGR from January 20,2019 to February 1,2020 were selected in study group,and 31 pregnant women with normal fetal development and matched with the age and the gestational weeks were selected in control group.All the women in the two groups underwent multi b-value DWI imaging,and the slow diffusion coefficient D,the fast diffusion coefficient D*,and the diffusion coefficient F were measured by IVIM model.Results:The placental pseudo diffusion coefficient D*(20.37±6.34 mm^(2)/s)and the perfusion fraction f(32.30%±4.17%)of the women in the study group were significantly lower than those(31.75±7.54 mm^(2)/s and 23.66%±3.87%)of the women in the control group(P=0.001),There was no significant difference in placental diffusion coefficient D(1.68±0.26 mm^(2)/s vs.1.61±0.22 mm^(2)/s)of the women between the two groups(P=0.64).Conclusion:The placental blood flow of the pregnant women with FGR can be observed by IVIM,which is helpful for early diagnosis of FGR.