生境成像用于肿瘤研究进展

Research progresses of habitat imaging for tumors

肿瘤细胞存活环境为具有复杂空间结构的生态系统,选择压力则对其具有决定性影响。生境成像(HI)可基于多参数MRI(mpMRI)生成高分辨率生境地图,反映肿瘤细胞及其微环境特性,进而显示肿瘤生长及治疗反应过程,有助于临床评估肿瘤。本文就HI用于肿瘤的研究进展进行综述。

The survival environment of tumor cells is an ecosystem with complex spatial structures,and the selective pressure brings decisive impact on it.Based on multiparameter MRI(mpMRI),habitat imaging(HI)can generate high-resolution tumor habitat maps to reflect the characteristics of tumor cells and the microenvironment,so as to clarify the growth and treatment response process,hence being helpful for clinical evaluation.The research progresses of HI for tumors were reviewed in this article.