巴戟天化学成分、药理作用及质量标志物预测分析

Chemical Components and Pharmacological Action of Bajitian(Radix Morindae Officinalis)and Predictive Analysis on Q-marker

巴戟天是我国“四大南药”之一,广泛分布在我国广西、广东、海南和福建等地。巴戟天中含蒽醌类、环烯醚萜类、糖类、挥发性物质、氨基酸类及微量元素等化合物,具补肾阳、强筋骨、祛风湿之功效。对巴戟天的化学成分和药理活性进行综述,基于中药质量标志物的核心概念,对巴戟天的质量标志物进行预测分析,认为巴戟天蒽醌类、环醚烯萜苷类及糖类成分是巴戟天的质量标志物。

Bajitian(Radix Morindae Officinalis)is one of the“four southern drugs”in China,widely distributed in Guangxi,Guangdong,Hainan and Fujian provinces.Bajitian(Radix Morindae Officinalis)contains anthraquinones,iridoid glycosides,saccharides,volatile substances,amino acids and trace elements and other compounds,with the effect of tonifying kidney Yang,strengthening muscles and bones and dispelling wind-dampness.In this paper,the chemical components and pharmacological effects of Bajitian(Radix Morindae Officinalis)were reviewed.Based on the core concept of quality markers of traditional Chinese medicine,it is considered that anthracene quinones,iridene terpenes and carbohydrates are the quality markers(Q-markers)of Bajitian(Radix Morindae Officinalis).