摘要
本文探讨超声定量分析技术预测食管胃底静脉曲张(EGV)出血危险度的价值。选取127例肝硬化门静脉高压患者为研究对象,随访3个月,失联2例,根据是否发生EGV出血分为发生组(60例)、未发生组(65例)。比较两组EGV严重程度、Child肝功能分级、肝脏剪切波速度(LSWV)、门静脉内径(PV)、脾脏剪切波速度值(SSWV)、脾脏指数(SI),并对数据进行统计学分析。结果显示,发生组LSWV、PV、SSWV、SI高于未发生组(P<0.05);LSWV、PV、SSWV、SI与EGV严重程度、Child肝功能分级呈正相关(P<0.05);以LSWV(X_(1))、PV(X_(2))、SSWV(X_(3))、SI(X_(4))作为协变量,得出联合预测因子表达式为:Logit(P)=-3.757+2.003×X_(1)+1.989×X_(2)+1.473×X_(3)+1.981×X_(4),其预测EGV出血危险度的曲线下面积(AUC)大于各原始协变量,为0.873,预测敏感度为78.33%,特异度为81.54%。超声定量分析技术检测LSWV、PV、SSWV、SI,可作为预测EGV出血危险度的一个方案,对临床预防性干预及外科手术方式具有一定指导作用。
This paper investigated the value of ultrasound quantitative analysis technology in predicting the bleeding risk of esophageal gastric varices(EGV).127 patients with cirrhotic portal hypertension were selected as the research objects.After 3 months of follow-up,2 patients lost contact.According to the presence or absence of EGV bleeding all patients were divided into the occurrence group(60 cases)and the non-occurrence group(65 cases).The severity of EGV severity,Child liver function classification,liver shear wave velocity(LSWV),portal vein diameter(PV),spleen shear wave velocity(SSWV),and spleen index(SI)were compared between the two groups,and the data were statistically analyzed.The results showed that the LSWV,PV,SSWV,and SI in the occurrence group were higher than those in the non-occurrence group(P<0.05).LSWV,PV,SSWV,and SI were positively correlated with EGV severity and Child liver function grade(P<0.05).The combined predictor expression with LSWV(X_(1)),PV(X_(2)),SSWV(X_(3)),SI(X_(4))as covariates was:Logit(P)=-3.757+2.003×X_(1)+1.989×X_(2)+1.473×X_(3)+1.981×X_(4),and its AUC for predicting EGV bleeding risk was 0.873 and greater than the original covariates,the predictive sensitivity was 78.33%,and the specificity was 81.54%.It can be seen that the detection of LSWV,PV,SSWV,and SI by ultrasonic quantitative analysis technology could be used as a plan to predict the risk of EGV bleeding,and it can play a certain guiding role in clinical preventive intervention and surgical method.
作者
刘伟
王贺
初晓燕
徐丽丽
王爱民
LIU Wei;WANG He;CHU Xiaoyan;XU Lili;WANG Aimin(Department of Gastroenterology,Chengde Central Hospital,Chengde 067000,Hebei,P.R.China;Department of General Surgery,Chengde Central Hospital,Chengde 067000,Hebei,P.R.China)
出处
《影像科学与光化学》
CAS
北大核心
2022年第5期1103-1107,共5页
Imaging Science and Photochemistry
关键词
超声
定量分析技术
食管胃底静脉曲张出血
出血危险度
ultrasound
quantitative analysis technique
esophagogastric varices bleeding
bleeding risk