肝血管瘤及不同肝癌病灶的能谱CT参数差异分析

Difference Analysis of Spectral CT Parameters between Hepatic Hemangioma and Different Hepatocellular Carcinoma Lesions

本研究探讨晚期肝癌介入术后残留病灶及早期新增病灶特征的能谱CT参数特征及意义。选取100例原发性肝癌患者(肝癌组),同时选取50例肝血管瘤患者作为对照(肝血管瘤组),原发性肝癌患者给予经皮肝动脉化疗栓塞(TACE)治疗。分析术前两组能谱CT参数差异,同时分析肝癌组术后病灶残留、复发及无残留或复发病灶能谱CT参数差异。肝癌组静脉期标准化碘浓度(VNIC)、动脉期标准化碘浓度(ANIC)、标准化碘浓度比率(ICratio)、动脉期曲线斜率、静脉期曲线斜率明显高于肝血管瘤患者(P<0.05)。复发病灶VNIC、ANIC、ICratio、动脉期曲线斜率和静脉期曲线斜率明显高于残留病灶、无残留或复发病灶(P<0.05)。能谱CT参数在肝血管瘤和肝癌中有明显差异,并在诊断原发性肝癌患者术后复发方面有一定应用价值。

This study investigated the characteristics and significance of spectral CT parameters of residual lesions and early new lesions after intervention for advanced liver cancer. 100 patients with primary liver cancer(liver cancer group) were selected, and 50 patients with hepatic hemangioma were selected as the control group(liver hemangioma group), and the patients with primary liver cancer were treated with percutaneous hepatic arterial chemoembolization(TACE). The differences of energy spectrum CT parameters between the two groups before operation were analyzed, the differences of energy spectrum CT parameters of residual and recurrent lesions and no residual or recurrent lesions in liver cancer group were analyzed. The venous standardized iodine concentration(VNIC), arterial standardized iodine concentration(ANIC), standardized iodine concentration ratio(ICratio), arterial curve slope and venous curve slope in liver cancer group were significantly higher than those in patients with hepatic hemangioma(P<0.05). VNIC, ANIC, ICratio, arterial phase curve slope and venous phase curve slope of recurrent lesions were significantly higher than those of residual lesions, no residual or recurrent lesions(P<0.05). There are significant differences in the energy spectrum CT parameters between hepatic hemangioma and liver cancer, and it has a certain application value in the diagnosis of postoperative recurrence of primary liver cancer patients.