摘要
During October 2021 and February 2022,nine pediatric patients with acute hepatitis of unknown origin were identifed in Children’s of Alabama[1].These patients were tested negative for hepatitis viruses;and several other etiologies of hepatitis in children including autoimmune hepatitis were ruled out[1].In a short period of time,the number of cases has surged in many countries;importantly,the rate has exceeded past annual incidence in various regions[2–4].On 23 April 2022,World Health Organization(WHO)has issued a warning on severe hepatitis of unknown origin in children[5].As of May 18,575 suspected cases have been identifed in Europe,United States of American(USA),Israel,India,Japan,and other countries;35 children required liver transplantation and 11 died[6].
基金
supported by Research on New Technology of Diagnosis and Treatment of Common Diseases in Children—Establishment and Application of Intelligent System for Rapid Diagnosis of Children’s Acute Diarrhea(Zhejiang Provincial Key R and D Program 2019C03037).
