血液抽吸联合射频消融治疗肝血管瘤患者疗效研究

Short-term efficacy of intratumor blood aspiration and radiofrequency ablation in the treatment of patients with hepatic hemangioma

目的观察比较血液抽吸联合射频消融(RFA)与肝动脉插管栓塞(TAE)治疗肝血管瘤(HCH)患者的疗效。方法2018年10月~2020年10月我科收治的102例HCH患者,其中56例接受TAE治疗,另46例接受血液抽吸联合RFA治疗。随访3个月。结果TAE组手术时间、术中出血量和住院日分别为(49.2±14.6)min、(13.4±3.7)mL和(3.4±1.6)d,而血液抽吸联合RFA治疗组分别为(57.5±18.9)min、(7.5±1.9)mL和(1.5±0.5)d,差异显著(P<0.05);在术后即刻和术后3个月,TAE治疗组瘤体容积分别为(49.2±22.5)mL和(31.4±15.7)mL,与RFA治疗的(49.1±22.3)mL和(31.2±15.5)mL比,无显著性差异(P>0.05),两组瘤体缩小率比较,也无显著性差异(P>0.05);术后,TAE组并发症发生率为17.9%,显著高于血液抽吸联合RFA治疗组的6.5%(P<0.05)。结论采用血液抽吸联合RFA治疗HCH患者能够减少术中出血和术后并发症的发生,但两组方法治疗效果相当。

Objective The purpose of this study was to compare the short-term efficacy of intratumor blood aspiration and radiofrequency ablation(RFA),and transcatheter arterial embolization(TAE)in the treatment of patients with hepatic hemangioma(HCH).Methods 102 patients with HCH were encountered in our hospital between October 2018 and October 2020,and the RFA after intratumor blood aspiration was conducted in 46 patients and the TAE was performed in 56 patients.All patients were followed-up for three months.Results The operative time,intraoperative blood loss and hospital stay in patients with TAE operation were(49.2±14.6)min,(13.4±3.7)mL and(3.4±1.6)days,significantly different compared to(57.5±18.9)min,(7.5±1.9)mL and(1.5±0.5)days,respectively,in patients receiving RFA after intratumor blood aspiration(P<0.05);at the moment immediately after operation and the end of three months,the tumor volumes in TAE-treated patients were(49.2±22.5)mL and(31.4±15.7)mL,not significantly different as compared to(49.1±22.3)mL and(31.2±15.5)mL in RFA-treated patients(P>0.05),and so were the tumor shrinkage rates in the two groups(P>0.05);after operation,the complications in TAE-treated patients was 17.9%,much higher than 6.5%(P<0.05)in RFA-treated patients.Conclusion The short-term efficacy of RFA after intratumor blood aspiration or TAE in the treatment of patients with HCH is good,and the RFA treatment has less post-operationally complications.