摘要
研究显示,银屑病患者体内存在大量异常的表观遗传改变,包括DNA甲基化、组蛋白修饰、非编码RNA调节等,提示表观遗传机制可能参与了银屑病的发病。该文综述银屑病表观遗传调控的研究进展。
Studies have shown a large number of aberrant epigenetic changes in patients with psoriasis,including DNA methylation,histone modification,non-coding RNA regulation,etc.,suggesting that epigenetic mechanisms may be involved in the occurrence of psoriasis.This review focuses on the recent progress in epigenetic regulation in psoriasis.
作者
刘晋
沈征宇
Liu Jin;Shen Zhengyu(Department of Dermatology,Shanghai Ninth People's Hospital,Shanghai JiaoTong University School of Medicine,Shanghai 200011,China)
出处
《中华皮肤科杂志》
CAS
CSCD
北大核心
2022年第9期825-829,共5页
Chinese Journal of Dermatology
基金
上海交通大学医学院附属第九人民医院“交叉”研究基金(JYJC201901)。
