孤独症谱系障碍共患强迫症的研究进展

Research progress of autism spectrum disorder comorbid with obsessive compulsive disorder

孤独症谱系障碍(ASD)是一组神经发育障碍性疾病,以社会交流、交往缺陷以及刻板重复性行为、兴趣和活动及感知觉异常为特征。强迫症是ASD常见的共患精神疾病之一,精准识别ASD的强迫症状和ASD共患强迫症的情况,尽早干预,有利于患儿的预后。然而,对于ASD共患强迫症的现象国内研究较少,现综合国外以往研究,对于ASD共患强迫症的流行病学、病因与神经机制研究、临床特征、评估诊断、干预和治疗方面的研究进展进行综述,从而早期识别共患强迫症表现,早期治疗改善患儿的预后。

Autism spectrum disorder(ASD)is a neurodevelopmental disorder characterized by difficulties in social communication and interaction,restricted and repetitive behaviors,interests and activities,and abnormal perception.Obsessive compulsive disorder(OCD)is one of the common comorbid mental diseases of ASD.Accurate identification of the obsessive-compulsive symptoms and OCD comorbidity of ASD and early intervention are essential for the prognosis of patients.However,there are few domestic studies on comorbid OCD in ASD.Based on previous studies abroad,the progress of research on the epidemiology,etiology and neural mechanism,clinical characteristics,evaluation,diagnosis,intervention and treatment of comorbid OCD in ASD was reviewed in this paper.It aims to identify the manifestations of OCD in ASD patients in the early stage and improve the prognosis of patients.