丹参多酚酸盐在老年冠心病患者中的疗效及对血脂的影响

Efficacy of Salvia Polyphenolic Acid Salt in Elderly Patients with Coronary Artery Disease and Its Effect on Blood Lipids

目的:探讨丹参多酚酸盐在老年冠心病患者中的疗效及对血脂的影响。方法:选择2020年1月-2021年1月徐州市中医院收治的老年冠心病患者86例,应用随机数字表法将其分为对照组和观察组,各43例。对照组行常规治疗,观察组在对照组基础上加用丹参多酚酸盐。对比两组治疗总有效率、血脂水平、炎症因子水平及中医症候积分。结果:治疗前,两组的各项指标比较,差异均无统计学意义(P>0.05)。治疗后,观察组的总胆固醇(TC)、甘油三酯(TG)、低密度脂蛋白胆固醇(LDL-C)、白细胞介素-6(IL-6)、超敏C反应蛋白(hs-CRP)及中医症候积分均低于对照组,治疗总有效率高于对照组,差异均有统计学意义(P<0.05)。结论:丹参多酚酸盐治疗老年冠心病效果优异,可调节血脂水平、抑制炎症因子,值得推广。

Objective:To investigate the efficacy of Salvia Polyphenolic Acid Salt in elderly patients with coronary heart disease and its effect on blood lipids.Method:A total of 86 elderly patients with coronary heart disease admitted to Xuzhou Hospital of Traditional Chinese Medicine from January 2020 to January 2021 were selected and divided into control group and observation group by random number table method,with 43 cases in each group.The control group was given conventional treatment,and the observation group was given Salvia Polyphenolic Acid Salt on the basis of the control group.The total effective rate,blood lipids levels,inflammatory factors levels and TCM syndrome score were compared between the two groups.Result:Before treatment,there were no significant differences in the indexes between the two groups (P>0.05).After treatment,the total cholesterol (TC),triacylglycerol (TG),low-density lipoprotein cholesterol (LDL-C),interleukin-6 (IL-6),high sensitivity C reactive protein (hs-CRP) and TCM syndrome score in the observation group were lower than those in the control group,and the total effective rate of treatment was higher than that of control group,the differences were statistically significant (P<0.05).Conclusion:Salvia Polyphenolic Acid Salt has excellent effect in the treatment of elderly coronary heart disease,which can regulate blood lipid level and inhibiting inflammatory factors,and is worthy of promotion.