疏肝健脾颗粒联合中药灌肠与柳氮黄吡啶治疗溃疡性结肠炎(肝郁脾虚型)的临床疗效对比

Comparison of Clinical Efficacy of Shuganjianpi Granule Combined with Traditional Chinese Medicine Enema and Sulfasalazine in the Treatment of Ulcerative Colitis(Liver Stagnation and Spleen Deficiency Type)

目的观察自制中成药物疏肝健脾颗粒联合中药灌肠、柳氮黄吡啶对溃疡性结肠炎(UC)的临床疗效差异。方法将60例轻、中度溃疡性结肠炎肝郁脾虚型患者随机分为两组:对照组30例,给予柳氮磺吡啶肠溶片口服。研究组30例,在对照组基础上给予疏肝健脾颗粒口服联合中药灌肠,观察并比较两组临床疗效。结果研究组总有效率较对照组更高(93.33%vs.73.33%),P<0.05。研究组治疗后在腹泻、腹痛、脓血便、里急后重方面的症状积分明显较对照组更低,P<0.05。结论对中医辨证属于肝郁脾虚型的轻、中度溃疡性结肠炎患者给予疏肝健脾颗粒联合中药灌肠可以明显提高临床有效率。

Objective To observe the clinical effect of the Shuganjianpi granules combined with traditional Chinese medicine enemas on UC of the liver stagnation and spleen deficiency type.Methods Sixty cases were randomly divided into two groups.30 cases in the treatment group were given the Shuganjianpi granules combined with traditional Chinese medicine enemas,and 30 cases in the control group were given sulfasalazine enteric-coated tablets,observed and copared the clinical efficacy of the two groups.Results The total effective rate of the study group was higher than that of the control group(93.33%vs.73.33%),P<0.05.After treatment,the symptom scores of diarrhea,abdominal pain,pus and blood in stool,tenesmus in the study group were significantly lower than those in the control group,P<0.05.Conclusion The Shuganjianpi granules combined with traditional Chinese medicine enemas on UC of the liver stagnation and spleen deficiency type was effective.