连通性的猕猴大脑PE细分分析及同源性研究

Analysis and Homology Research of Connected Macaque’s Brain PE Segmentation

基于白质纤维束的解剖连接来分割猕猴的PE,通过概率纤维追踪定义了两个PE亚区,一个位于前侧,另一个位于背侧。同时为PE区和PE亚区绘制了具有19个预定义同源目标脑区的连通性指纹,验证了PE区及所划分出的PE亚区在连接模式上与人类5l区相似,并推断PE前侧亚区与5l区同源。研究所得到的分割结果有助于PE影像连接分析,并为其在亚区层面上的信息交互和整合提供新的见解,对猕猴模型研究的精准展开和人类高级运动功能的探索具有理论意义和应用价值。

To segment PE in macaques based on the anatomical connections of white matter fiber tracts,two PE subregions were defined,one anterior and the other dorsal,by probabilistic fiber tracing.At the same time,a connectivity fingerprint map was drawn with 19 predefined homologous target brain regions for PE and PE subregions.It was verified that PE and PE subregions are similar to human 51 in connection pattern,and inferred that the PE anterior subregion is homologous to the 51.The segmentation results obtained in this study are helpful for PE image connection analysis,and provide new insights into its information interaction and integration at subregional level.This work has important theoretical significance and application value for the precise development of the research on macaque model and the exploration of the unique advanced motor functions of humans.