CT评估和预测局部进展期胰腺癌综合治疗疗效的研究进展

Research progress of CT in evaluating and predicting the efficacy of comprehensive treatment for locally advanced pancreatic cancer

多学科协作的综合治疗已成为局部进展期胰腺癌(LAPC)主要的治疗方式。CT动态增强扫描是对治疗后疗效评估和预测的重要方式,但依据实体肿瘤反应评估标准(RECIST)1.1版中的评估标准,CT动态增强扫描无法准确反映肿瘤内部病理变化。目前已有较多研究探索CT影像组学、能谱CT、CT灌注成像等对LAPC综合治疗的疗效评估和预测。就多种CT技术对LAPC综合治疗疗效评估和预测的研究进展予以综述。

Multidisciplinary comprehensive treatment has become the main treatment method for locally advanced pancreatic cancer(LAPC).CT dynamic enhancement scan is an important modality for the assessment and prediction of treatment efficacy.However,based on the Response Evaluation Criteria in Solid Tumors(RECIST)version 1.1,CT dynamic enhancement scan cannot accurately reflect the pathological changes within the tumor.Many studies have explored the efficacy and outcome prediction for the LAPC comprehensive treatment by means of CT radiomics,energy spectrum CT,and CT perfusion imaging.The progresses of research on above mentioned aspects are reviewed.