胶体渗透压的影响因素、测量方法及临床应用

Influence Factors,Measurement Methods and Clinical Application of Colloid Osmotic Pressure

胶体渗透压是血浆及组织渗透压的重要组成成分,由白蛋白、球蛋白、纤维蛋白等大分子物质形成,在调节血管内外水平衡及维持血浆容量方面起重要作用。近年来越来越多研究关注到胶体渗透压在组织水肿、外科手术、休克治疗过程中的重要作用,其数值受多种因素影响,监测胶体渗透压的变化可能是预测患者预后及指导临床治疗中液体管理的重要手段。本文就胶体渗透压的影响因素、测量方法及其在临床的应用等几方面作一综述,以期为临床治疗多种疾病提供参考。

Colloidal osmotic pressure is an important component of plasma and tissue osmotic pressure,which is formed by macromolecules such as albumin,globulin and fibrin,and plays an important role in regulating the internal and external water balance of blood vessels and maintaining plasma volume.In recent years,more and more studies have paid attention to the important role of colloid osmotic pressure in tissue edema,surgical operation and shock treatment,and its value is affected by many factors.Monitoring the change of colloid osmotic pressure may be an important means to predict the prognosis of patients and guide fluid management in clinical treatment.This paper reviews the influencing factors,measurement methods and clinical application of colloid osmotic pressure in order to provide reference for clinical treatment of various diseases.