2型糖尿病患者抗糖尿病药物治疗与血糖控制情况分析

Analysis of antidiabetic drug treatment and blood sugar control in patients with type 2 diabetes

目的探究2型糖尿病患者抗糖尿病药物治疗与血糖控制情况。方法选取2019年1月至2020年1月本院收治的80例2型糖尿病患者作为研究对象,根据3个月内的降糖药物使用情况分为参照组与研究组,每组40例。参照组采用胰岛素治疗,研究组采用抗糖尿病药物治疗,比较两组治疗前后血糖指标、血糖达标率与低血糖发生率。结果治疗后,两组空腹血糖(FPG)、餐后2 h血糖(2 h PG)及糖化血红蛋白(HbAlc)水平均低于治疗前,且研究组低于参照组,差异有统计学意义(P<0.05)。研究组血糖达标率、低血糖发生率均低于参照组,差异有统计学意义(P<0.05)。结论采用抗糖尿病药物口服方案治疗2型糖尿病患者的临床疗效优于胰岛素注射方案,可有效提升患者血糖达标率,且不易发生低血糖,值得临床推广应用。

Objective To investigate the status of antidiabetic drug treatment and blood sugar control in patients with type 2 diabetes.Methods 80 patients with type 2 diabetes who were admitted to our hospital from January 2019 to January 2020 were selected as the study subjects,they were divided into reference group and study group according to the use of hypoglycemic drugs within 3 months,with 40 cases in each group.The control group was treated with insulin,and the study group was treated with antidiabetic drugs,the blood glucose indexes,the rate of reaching the blood glucose standard and the incidence of hypoglycemia were compared between the two groups.Results After treatment,the levels of fasting plasma glucose(FPG),2 hour postprandial glucose(2 h PG)and glycosylated hemoglobin Alc(HbAlc)in both groups were lower than those before treatment,and the study group were lower than those of the reference group,and the difference was statistically significant(P<0.05).The blood glucose up-tostandard rate and the incidence of hypoglycemia in the study group were lower than those in the reference group,and the difference was statistically significant(P<0.05).Conclusion The clinical efficacy of oral antidiabetic drug treatment in patients with type 2 diabetes is better than that of insulin injection,which can effectively improve the rate of blood sugar compliance,and is less prone to hypoglycemia,which is worthy of clinical application.