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阿托西班联合黄体酮阴道栓剂治疗先兆早产的临床效果及对妊娠结局的影响 被引量:4

Clinical Effect of Atoxiban Combined with Progesterone Vaginal Suppository in the Treatment of Threatened Preterm Birth and the Influence on Pregnancy Outcomes
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摘要 目的探讨阿托西班联合黄体酮阴道栓剂治疗先兆早产的临床效果及对妊娠结局的影响。方法选择2020年1月至2021年12月我院收治的100例先兆早产患者,根据患者入院顺序平均分为两组。对照组仅应用阿托西班治疗,观察组采用阿托西班联合黄体酮阴道栓剂治疗。比较两组的临床疗效、妊娠结局及不良反应情况。结果观察组治疗总有效率为96.00%,高于对照组的78.00%(P<0.05)。观察组延长孕期天数、新生儿体质量及新生儿Apgar评分均高于对照组(P<0.05)。两组的不良反应发生率比较差异无统计学意义(P>0.05)。结论阿托西班联合黄体酮阴道栓剂治疗先兆早产的临床效果显著,能够改善妊娠结局,安全性较高。 Objective To explore the clinical effect of atoxiban combined with progesterone vaginal suppository in the treatment of threatened preterm birth and the influence on pregnancy outcomes.Methods 100 patients with threatened preterm birth admitted to our hospital from January 2020 to December 2021 were divided into two groups equally.The control group was only treated with atoxiban,and the observation group was treated with atoxiban combined with progesterone vaginal suppository.The clinical efficacy,pregnancy outcomes and adverse reactions were compared between the two groups.Results The total effective rate of treatment in the observation group was 96.00%,higher than 78.00% in the control group(P<0.05).The days of prolonged pregnancy,neonatal body mass and neonatal Apgar score in the observation group were higher than those in the control group(P<0.05).No statistical difference was found in the incidence of adverse reactions between the two groups(P>0.05).Conclusions Atoxiban combined with progesterone vaginal suppository in the treatment of threatened preterm birth has significant clinical effect can improve the pregnancy outcomes,with higher safety.
作者 荣楚雪 朱燕 RONG Chuxue;ZHU Yan(Department of Obstetrics and Gynecology,Xinyang Central Hospital,Xinyang 464000,China)
出处 《临床医学工程》 2022年第9期1231-1232,共2页 Clinical Medicine & Engineering
关键词 阿托西班 黄体酮阴道栓剂 先兆早产 临床效果 安全性 Atoxiban Progesterone vaginal suppository Threatened preterm birth Clinical effect Medication safety
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