右美托咪定复合丙泊酚在异位妊娠手术麻醉中的应用及对患者应激风险的影响

Application of Dexmedetomidine Combined with Propofol in the Anesthesia of Ectopic Pregnancy Surgery and the Influence on Stress Risk of Patients

目的探讨右美托咪定复合丙泊酚在异位妊娠手术麻醉中的应用效果及对患者应激风险的影响。方法选取2020年3月至2021年3月我院收治的110例异位妊娠手术患者,随机分为两组各55例。对照组采用丙泊酚麻醉,观察组采用右美托咪定复合丙泊酚麻醉。比较两组的相关临床指标、心率(HR)、平均动脉压(MAP)及不良反应发生情况。结果观察组的唤醒睁眼时间、意识恢复时间及定向力恢复时间短于对照组(P<0.05)。T_(1)时,两组的HR降低,观察组的HR高于对照组(P<0.05)。T_(1)、T_(2)时,两组的MAP降低,观察组的MAP高于对照组(P<0.05)。观察组术后不良反应发生率为7.27%,低于对照组的21.82%(P<0.05)。结论右美托咪定复合丙泊酚在异位妊娠手术麻醉中的应用效果显著,可降低应激风险,患者术后恢复快。

Objective To explore the application effect of dexmedetomidine combined with propofol in the anesthesia of ectopic pregnancy surgery and the influence on stress risk of patients.Methods 110 patients with ectopic pregnancy surgery in our hospital from March 2020 to March 2021 were randomly divided into two groups,with 55 cases in each group.The control group was given propofol for anesthesia,and the observation group was given dexmedetomidine combined with propofol for anesthesia.The related clinical indicators,heart rate(HR),mean arterial pressure(MAP)and adverse reactions were compared between the two groups.Results The wake-up eye opening time,consciousness recovery time and orientation recovery time of the observation group were shorter than those of the control group(P<0.05).At T_(1),the HR of the two groups decreased,but the HR of the observation group was higher than that of the control group(P<0.05).At T_(1) and T_(2),the MAP of the two groups decreased,but the MAP of the observation group were higher than those of the control group(P<0.05).The incidence of postoperative adverse reactions in the observation group was 7.27%,lower than 21.82% in the control group(P<0.05).Conclusions Dexmedetomidine combined with propofol has significant effect in the anesthesia of ectopic pregnancy surgery,can reduce the stress risk and make patients recover quickly after surgery.