头孢他啶联合左氧氟沙星治疗尿路感染的临床效果分析

Analysis on Clinical Effect of Ceftazidime Combined with Levofloxacin in the Treatment of Urinary Tract Infection

目的分析头孢他啶联合左氧氟沙星治疗尿路感染的临床效果。方法选取2018年2月至2020年2月我院收治的76例尿路感染患者,随机分为实验组(n=38)和对照组(n=38)。对照组采用左氧氟沙星治疗,实验组采用头孢他啶联合左氧氟沙星治疗。比较两组的临床疗效、免疫指标[免疫球蛋白A(IgA)、免疫球蛋白M(IgM)]及不良反应发生率。结果实验组治疗总有效率为94.74%,高于对照组的71.05%(P<0.05)。治疗后,两组的IgA、IgM水平均高于治疗前,且实验组的IgA、IgM水平高于对照组(P<0.05)。两组的不良反应发生率(5.26%vs.15.79%)比较无统计学差异(P>0.05)。结论头孢他啶联合左氧氟沙星治疗尿路感染可明显提升临床疗效,有效调节患者机体免疫功能,且安全性较高。

Objective To analyze the clinical effect of ceftazidime combined with levofloxacin in the treatment of urinary tract infection.Methods 76 patients with urinary tract infection admitted to our hospital from February 2018 to February 2020 were selected and randomly divided into experimental group(n=38)and control group(n=38).The control group was treated with levofloxacin,and the experimental group was treated with ceftazidime combined with levofloxacin.The clinical efficacy,immune indicators[immunoglobulin A(IgA),immunoglobulin M(IgM)]and the incidence of adverse reactions were compared between the two groups.Results The total effective rate of treatment in the experimental group was 94.74%,higher than 71.05% in the control group(P<0.05).After treatment,the IgA and IgM levels of the two groups were higher than those before treatment,and the IgA and IgM levels of the experimental group were higher than those of the control group(P<0.05).No statistical difference was found in the incidence of adverse reactions(5.26%vs.15.79%)between the two groups(P>0.05).Conclusions Ceftazidime combined with levofloxacin in the treatment of urinary tract infection can significantly improve the clinical efficacy,and effectively regulate the immune function of patients,with higher safety.