瑞芬太尼复合丙泊酚应用于腹腔镜胆囊切除麻醉中对血流动力学的影响分析

Effect Analysis of Remifentanil Combined with Propofol on Hemodynamics of Laparoscopic Cholecystectomy

目的探讨瑞芬太尼复合丙泊酚应用于腹腔镜胆囊切除麻醉中对血流动力学的影响。方法抽取江苏省连云港市灌南县人民医院2018年3月-2019年2月收治的52例腹腔镜胆囊切除术患者作为观察对象,随机数字法分为两组,对照组患者行舒芬太尼+丙泊酚进行麻醉,观察组患者行瑞芬太尼+丙泊酚进行麻醉,观察两组患者麻醉中血流动力的影响。结果麻醉后,观察组患者5min及10min后镇痛效果明显优于对照组(P<0.05);麻醉后,相较于对照组,观察组患者的血压及心率明显平稳(P<0.05);麻醉后,观察组与对照组患者的不良反应发生率分别为7.69%、23.08%,两组对比无显著差异(P>0.05)。两组呼吸恢复、拔管、睁眼及回病房时间相比,观察组明显短于对照组(P<0.05)。结论瑞芬太尼复合丙泊酚在腹腔镜胆囊切除麻醉中有重要作用,能控制正常血压及心率,对镇痛有显著效果,能够缩短患者术后恢复时间,建议推广应用。

Objective To investigate effect of remifentanil combined with propofol on hemodynamics in laparoscopic cholecystectomy.Methods The paper chose 52 patients with laparoscopic cholecystectomy admitted to Lianyungang City Guannan County People's Hospital from March 2018 to February 2019,and divided them into two groups randomLy.Control group was anesthetized with sufentanil+propofol,and observation group with remifentanil+propofol.Effect of hemodynamics between two groups was observed.Results After anesthesia,analgesic effect of observation group after 5min and 10min was significantly better than control group(P<0.05).After anesthesia,blood pressure and heart rate of observation group were more significantly stable than control group,(P<0.05).After anesthesia,incidence of adverse reactions in observation group and control group were 7.69%and 23.08%respectively,there was no significant difference between two groups(P>0.05).Time of respiratory recovery,extubation,eye opening and return to ward in observation group was significantly shorter than control group(P<0.05).Conclusion Remifentanil combined with propofol plays an important role in laparoscopic cholecystectomy anesthesia,can control normal blood pressure and heart rate,with significant effect on analgesia,can shorten postoperative recovery time of patients,which is recommended to promotion and application.