PsA及中重度PsV患者的超声特征及其临床意义

Ultrasonic Characteristics and Clinical Significance of Patients with PsA and Moderate to Severe PsV

目的探讨银屑病关节炎(psoriatic arthritis,PsA)与中重度寻常型银屑病(psoriasis vulgaris,PsV)患者的超声特征及其临床意义。方法选取2019年1月~2021年6月北京市海淀医院收治的40例PsA患者及同期收治的40例中重度PsV患者,两组均行肌骨超声检查,评估银屑病累及关节情况。结果PsA组患者年龄、病程均大于中重度PsV组(P<0.05),且关节疼痛患者比例更高(P<0.05)。PsA组骨侵蚀、滑膜炎(活跃期)、附着点炎、滑膜增厚、关节间隙变窄患者占比均高于中重度PsV组(P<0.05)。结论PsA组及中重度PsV组关节超声异常比较均较高,可以将关节阳性改变作为PsV是否进展到PsA的判断依据之一,应在银屑病患者中常规筛查关节超声,早期发现关节异常改变,为进一步的临床治疗提供影像支持。

Objective To investigate the ultrasonic characteristics and clinical significance of patients with psoriatic arthritis(PsA)and moderate to severe psoriasis vulgaris(PsV).Methods 40 patients with PsA and 40 patients with moderate to severe PsV who were admitted and treated in Beijing Haidian hospital from January 2019 to June 2021 were selected.Both groups were examined by muscle and bone ultrasound to evaluate the involvement of joints in psoriasis.Results The age and disease duration of the patients in the PsA group were higher than those in the moderate to severe PsV group(P<0.05),and the proportion of patients with joint pain in the patients in the articular psoriasis group was higher(P<0.05).The proportion of patients with bone erosion,synovitis(active phase),enthesitis,synovial thickening and joint space narrowing in the PsA group was higher than that in the moderate to severe PsV group(P<0.05).Conclusion In this study,the patients with PsA and patients with moderate to severe PsV have higher joint ultrasound abnormalities,and the positive changes in joints can be used as one of the basis to judge whether PsV has progresses to PsA.Joint ultrasound should be routinely screened in patients with psoriasis to detect abnormal joint changes early and provide imaging support for further clinical treatment.