食管胃结合部腺癌:是独立的实体肿瘤吗?

s adenocarcinoma of esophagogastric junction an independent distinct entity?

食管胃结合部(esophagogastric junction, EGJ)癌是指侵及EGJ, 距离EGJ近端或远端5 cm以内的恶性肿瘤。随着对幽门螺杆菌的重视及生活习惯的改变, 目前胃癌及食管癌的发病率有所下降, 而EGJ癌的发病率在世界各地呈逐年上升的趋势。由于此病跨域食管和胃, 对于其属于食管还是胃, 或者是否属于独立的实体肿瘤成为近年热点。本文献将通过其定义、病因、危险因素、内镜特征等, 探讨此病不同部位的特点, 以帮助临床及科研人员深入了解, 并提高肿瘤的治愈率。

Esophagogastric junction(EGJ)carcinoma refers to a malignant tumor involving EGJ and within 5 cm from the proximal or distal part of EGJ.With the attention paid to Helicobacter pylori and the change of living habits,the incidences of gastric cancer and esophageal cancer have decreased,while the incidence of EGJ cancer is increasing year by year all over the world.Because this disease locates on the esophagus and stomach,that whether it is territory of the esophagus or stomach or an independent region has become a hot topic in recent years.This paper discusses the characteristics of different parts of the disease through its definition,etiology,risk factors,endoscopic characteristics,etc.,so as to help clinical and scientific researchers have a deeper understanding of the disease and improve the cured rate.