舒血宁注射液联合早期作业治疗脑卒中恢复期临床研究

Clinical Study on Shuxuening Injection Combined with Early Nursing for Stroke in Rehabilitation Period

目的:观察舒血宁注射液联合早期作业治疗脑卒中恢复期患者的临床效果。方法:选取脑卒中恢复期患者120例作为研究对象,随机分为观察组和对照组各60例。2组均给予临床常规治疗措施,对照组联合早期作业治疗,观察组在对照组的基础上加用舒血宁注射液治疗。治疗1个月后,观察比较2组治疗前后改良Rankin量表(mRS)评分及Barthel (BI)指数。随访3个月,观察比较2组死亡情况及肢体障碍、语言障碍、记忆力差等后遗症发生率。结果:治疗前,2组mRS评分、BI指数比较,差异无统计学意义(P>0.05);治疗后,2组mRS评分较治疗前降低(P<0.05),BI指数较治疗前升高(P<0.05),且观察组2项指标改善较对照组更显著(P<0.05)。随访3个月,2组无死亡病例;观察组后遗症发生率为6.67%,对照组为10.00%,2组比较,差异无统计学意义(P>0.05)。结论:舒血宁注射液联合早期作业练习治疗脑卒中恢复期患者,可显著促进神经功能恢复,增强其日常生活自理能力,且后遗症发生率相对较低。

Objective:To observe the clinical effect of Shuxuening injection combined with early nursing for stroke patients in rehabilitation period.Methods:A total of 120 cases of stroke patients in rehabilitation period were selected as the study subjects and randomly divided into the observation group and the control group,with 60 cases in each group.Both groups were given clinical routine treatment measures;the control group was additionally given early exercise,and the observation group was additionally treated with Shuxuening injection based on the nursing of the control group.Both groups were treated for one month.Before and after treatment,the scores of modified Rankin Scale(mRS) and Barthel Index(BI) in the two groups were observed and compared.After three-month follow-up,the death status and incidences of sequelae including limb disorder,language disorders,and Poor memory in the two groups were observed and compared.Results:Before treatment,there was no significant difference being found in the comparison of mRS scores and Bl values between the two groups(P>0.05).After treatment,the mRS scores in the two groups were decreased when compared with those before treatment(P<0.05),and Bl values were increased(P<0.05);the improvement of the above two indexes in the observation group was more significant than in the control group(P<0.05).After three-month follow-up,there was no dead case in the two groups;the incidence of sequelae was 6.67% in the observation group and 10.00% in the control group,there being no significance in the difference(P>0.05).Conclusion:Shuxuening injection combined withearly exercise for stroke patients in rehabilitation period can effectively improve the recovery of neurological function,and enhance their activities of daily living,with low incidence of sequelae.