丹参酮ⅡA注射液联合美沙拉嗪治疗溃疡性结肠炎35例疗效观察

Effect Observation of TanshinoneⅡA Injection Combined with Mesalazine in the Treatment of 35 Cases of Ulcerative Colitis

目的:观察丹参酮ⅡA注射液联合美沙拉嗪治疗溃疡性结肠炎的疗效。方法:将70例溃疡性结肠炎患者随机分为观察组和对照组,每组35例。观察组患者采用丹参酮ⅡA注射液联合美沙拉嗪治疗,对照组患者单纯采用美沙拉嗪治疗,比较2组患者的疗效及不良反应发生率。结果:观察组患者的治疗总有效率明显高于对照组(P<0.05),不良反应发生率明显低于对照组(P<0.05)。结论:丹参酮ⅡA注射液联合美沙拉嗪治疗溃疡性结肠炎,可明显降低患者的不良反应发生率,效果显著。

Objective To observe the efficacy of tanshinoneⅡA injection combined with mesalazine in the treatment of ulcerative colitis(UC).Methods 70patients with UC were randomly divided into observation group(n=35,treated with tanshinoneⅡA injection combined with Mesalazine)and control group(n=35,treated with mesalazine alone),the efficacy and adverse reaction incidence of the two groups were compared.Results The total effective rate of the observation group was significantly higher than that of the control group(P<0.05),and the incidence of adverse reactions was significantly lower than that of the control group(P<0.05).Conclusion TanshinoneⅡA injection combined with mesalazine can significantly reduce the incidence of adverse reactions in patients with ulcerative colitis.The effect is remarkable.