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The role of intestinal flora in the immune system

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摘要 The intestinal tract is the body's biggest digestive organ.Many microbes,including bifidobacteria,Lactobacillus,Escherichia coli,Enterococcus,Clostridium perfringens,and Pseudomonas,are always present in the intestinal tract.The digestive tract has evolved localized immunological features to defend the body from potential invaders.Its structure,function,and milieu are considerably distinct from common central and peripheral immune organs and account for these characteristics.The intestinal flora and its products provide a microenvironment in the gut that has a significant impact on the area's immune function.In turn,various disorders regulate and alter the kinds of gut microorganisms.The gut flora and immune system are constantly communicating with one another.Additionally,the intestinal microenvironment may be reconstructed with probiotics or microbiota transplantation.This assists in restoring immunological homeostasis and treating or preventing illness.This manuscript examines how the intestinal flora influences the development and spread of illnesses,which in turn impacts intestinal immunity.We also discuss how improved immune function influences the general and particular immune systems.As a method of disease prevention and treatment,we also discuss how modifying the microenvironment affects the proliferation,differentiation,and release of immune cells in the intestinal region.Finally,we discuss how human behaviors influence gut microorganisms.
出处 《Microenvironment & Microecology Research》 2022年第3期9-14,共6页 微环境与微生态学研究(英文)
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