金钱草中有害元素的测定及污染等级的分析

Determination and pollution grade analysis of harmful elements in Lysimachia christinae

目的检测金钱草中铅、镉、汞、砷、铜、锌、铬等元素的含量,并进行污染等级分析。方法采用电感耦合等离子体质谱测定金钱草中的7种元素,用单项指数法和综合指数法对其进行污染等级分析。结果7种元素在各自浓度范围内呈良好的线性关系,样品加标回收率为84.5%~109.5%,RSDs为2.30%~5.10%。与2020年版《中国药典》中规定的限量值进行比较,19批样品中铬元素超标、7批样品中锌元素超标,超标率分别为100%、36.8%,其余元素的含量均未超标;单项指数从大到小排序为铬、锌、镉、汞、铜、砷、铅,综合污染等级均值为轻度污染及以上。结论金钱草主要受铬元素污染,其次是锌元素;研究结果可为金钱草中重金属元素限量标准的起草提供基础数据。

OBJECTIVE To detect content of Pb,Cd,Hg,As,Cu,Zn,and Cr in Lysimachia christinae,and to analyze the pollution level.METHODS Seven kinds of elements in L.christinae were determined by Inductively coupled plasma mass spectrometry and analyzed by single index and comprehensive index.RESULTS The seven heavy metal elements showed good linearity in their respective concentration ranges.The recoveries of the samples were 84.5%-109.5%,and the RSDs were 2.30%-5.10%.Comparing the measured results of heavy metal elements with the limit values stipulated in the 2020 edition of the Chinese Pharmacopoeia and other standards,the Cr element in 19 batches of samples exceeded the standard,and the Zn element in 7 batches of samples exceeded the standard.The exceeding rates were 100.0%and 36.8%,respectively.The content of other heavy metal elements did not exceed the standard.The order of individual index from large to small was Cr,Zn,Cd,Hg,Cu,As,and Pb,and the average comprehensive pollution level was light pollution and above.CONCLUSION L.christinae is mainly polluted by Cr,followed by Zn;this study can provide basic data for drafting of the limit standard for heavy metal elements in L.christinae.