加味五苓散配合穴位贴敷治疗阳虚水盛型肝硬化腹水的临床疗效观察

The observation on the curative effect of Jiawei Wuling powder combined with acupoint application in the treatment of water diffusion yang deficiency of hepatic ascites

目的 探讨加味五苓散配合穴位贴敷治疗肝硬化腹水的临床疗效及其安全性.方法 选取本院60例肝硬化腹水病人,进行随机数字分组,分为对照组(30例)和观察组(30例).对照组单纯予以常规西医综合疗法,观察组在西医的基础上予中药加味五苓散+穴位贴敷辅助治疗.治疗1个月,观察各组临床疗效、中医证候积分、实验室指标和不良反应,并进行对比研究.结果 两组在治疗前后,肝功能、凝血功能、肝纤维化指标的改善、腹水的消退均有显著差异(P<0.05),且观察组优于对照组(P<0.05).两组在治疗前后腹围、体重、平均24 h尿量有显著差异(P<0.05),且观察组优于对照组(P<0.05).结论 加味五苓散配合穴位贴敷治疗阳虚水盛型肝硬化腹水,疗效确切,具有安全、有效的特点,值得在临床推广.

Objective To observe the clinical eficacy and safety evaluation of jawei Wuling powder combined with acupoint application in the treatment of hepatic ascites.Methods The inclusion and exclusion criteria for this study were as followes,60 patients with liver cirrhosis were randomly selected to meet the conditions of the digital packet and were divided into Chinese and Westerm combination group and Western medicine Group,with 30 cases in each group.The westem medicine group was given conventional western medicine and the Chinese and Western combination group was given auxiliary treatment of Chinese medicine Jiawei Wuling powder plus acupoint application on the basis of western medicine.Patients were continuously treated for 1 months.Clinical ffects,Traditional Chinese Medicine syndrome score(hereinafer clled TCM score),laboratory index and adverse reactions were observed in each group,and a comparative study was performed.Results Before and after treatment,the improvement of liver function,coagulation function,hepatic fibrosis index and ascites regression between the two groups were significantly different(P<0.05)and the Chinese and Westermn medicine combination group was better than the Western Medicine Group(P<0.05).Before and afer treatment,the abdominal circumference,body weight and mean 24-hour urine volume between the two groups were significantly different(P<0.05),and the Chinese and Western medicine combination group was better than the Westerm Medicine Group(P<0.05).Conclusion Jiawei Wuling powder combined with acupoint application in the treatment of water difusion yang deficiency of hepatic ascites has exact curative effect.It is safe and effective,and is worth popularizing in clinic.