摘要
A new conceptual model has been proposed for Parkinson's disease(PD)pathogenesis,which can be divided into triggering,facilitating,and aggravating processes[1].Mitochondria are believed to participate in all three phases:pesticides(one of the definite triggers in PD pathogenesis)inhibit mitochondrial complex I(MCI).
基金
This insight article,was,supportedby the National Natural Science Foundation of China(32170984 and 31871049)
the Excellent Innovative Team of Shandong Province
the Taishan Scholars Construction Project.