睾丸部分切除术治疗良性睾丸肿瘤:一项单中心研究

Partial orchiectomy in the treatment of testicular benign tumor: results from a single-center study

目的评估睾丸部分切除术(PO)治疗良性睾丸肿瘤的临床疗效和结局。方法回顾性分析2013年12月至2021年7月在本院行睾丸部分切除术的16例良性睾丸肿瘤的临床资料。记录患者的基本资料、手术时间、住院时间,分析肿瘤标志物、病理和并发症情况,比较睾丸囊性与实性病变的临床特点。结果睾丸囊性病变11例,包括睾丸表皮样囊肿5例,睾丸囊肿6例;睾丸实性病变5例,包括畸胎瘤2例,睾丸间质细胞瘤、异位骨化和结核性肉芽肿各1例。与睾丸实性病变相比,睾丸囊性病变的最大直径显著增大,差异有统计学意义(P=0.011)。睾丸囊性与实性病变患者的年龄、病程、手术时间、肿瘤标志物比较,差异均无统计学意义(均P>0.05)。随访(40.5±28.8)个月,所有患者无睾丸附睾炎、尿路感染、伤口感染等并发症发生。结论良性睾丸肿瘤的病理类型多种多样,睾丸囊性病变的大小一般大于睾丸实性病变,PO是一种在技术上可行、安全、能有效治疗良性睾丸肿瘤的方法。

Objective To assess the clinical effect and outcomes of partial orchiectomy(PO)in the management of testicular benign tumor.Methods The clinical data of 16 patients with benign testicular tumors who underwent partial orchiectomy in our hospital from December 2013 to July 2021 were retrospectively analyzed.The basic data,operation time and hospital stay of the patients were recorded.Tumor markers,pathology and complications were analyzed,and the clinical characteristics of testicular cystic and solid lesions were compared.Results There were 11 cases of testicular cystic lesions,including 5 cases of testicular epidermoid cyst and 6 cases of testicular cyst.There were 5 cases of testicular solid lesions,including 2 cases of teratoma,1 case of testicular stromal cell tumor,1 case of heterotopic ossification and 1 case of tuberculous granuloma.The maximum diameter of testicular cystic lesions was significantly larger than that of testicular solid lesions(P=0.011).There were no significant differences in age,disease duration,operation time and tumor markers between patients with testicular cystic lesions and solid lesions(all P>0.05).During the follow-up of(40.5±28.8)months,no complications such as testicular epididymitis,urinary tract infection and wound infection occurred.Conclusions The pathological types of testicular benign tumors are various.Generally,the sizes of testicular cystic lesions are larger than testicular solid lesions.PO is a technically feasible,safe,and effective treatment method for testicular benign tumor.