新型冠状病毒疫苗加强免疫策略的进展及专家建议

Expert recommendations on booster immunization strategies of 2019-nCoV vaccines

由新型冠状病毒(2019-nCoV)引起的疫情自2019年底出现以来,至今仍在全球肆虐,并持续威胁全球的公共卫生安全和经济发展。新型冠状病毒疫苗(新冠疫苗)是预防新型冠状病毒肺炎的有效手段,但研究表明疫苗接种诱导的免疫保护效果随着时间的延长不断下降,而一些新的、免疫逃逸强的变异株不断出现,因此亟需完成加强免疫接种以提高保护力。目前我国已有基于多种技术平台的新冠疫苗获批上市,因此特撰写此新冠疫苗序贯接种策略,为2019-nCoV及其变异株的防控提供专家建议。

Since the end of 2019,the COVID-19 caused by 2019-nCoV has emerged and the pandemic ravaged the world,which seriously threatens global public health security and economic development.2019-nCoV vaccine is an effective weapon to combat the viral infection,however,studies have shown that vaccine-induced immune protection decreases over time,coupled with some novel and immune escape variants continual emerging.Therefore,it is urgent to complete booster immunization to improve protection.At present,2019-nCoV vaccines based on a variety of technical platforms have been approved and available in China.Therefore,we developed this sequential vaccination strategy guide to provide documentation guidance for the prevention and control of the epidemic caused by 2019-nCoV and its variant strains.