特瑞普利单抗致免疫相关皮肤严重不良反应一例

Immune-related skin severe adverse reaction caused by Toripalimab:a case report

3级皮肤不良反应是特瑞普利单抗相关皮肤不良反应中少见但严重的不良反应,本文报道1例66岁胰腺癌患者,在特瑞普利单抗联合白蛋白结合型紫杉醇治疗后出现严重的皮肤不良反应,暂停用药并予以激素治疗后症状逐渐缓解,后患者未再重启免疫治疗。

Grade 3 skin adverse reaction is a rare but severe adverse reaction in Toripalimab-related skin adverse reaction.This article reported a 66-year-old patient with pancreatic cancer who developed severe skin adverse reaction after application of Toripalimab combined with Albumin-bound Paclitaxel.The symptoms were gradually relieved after the drug was suspended and hormone therapy was given,and the patient did not restart immunotherapy after that.