宫颈癌螺旋断层放疗与容积旋转调强放疗的剂量学比较

Dosimetric Comparison Between Helical Tomotherapy and Volumetric Rotary Intensity-modulated Radiotherapy for Cervical Cancer

目的:探讨宫颈癌螺旋断层放疗与容积旋转调强放疗的剂量学差异及优势。方法:选择2021年1月至2022年1月蚌埠医学院第一附属医院收治的20例宫颈癌患者,均实施螺旋断层放疗(数据作为对照组),治疗4周后,调整为容积旋转调强放疗(数据作为观察组)。比较两种放疗方式的剂量学差异。结果:观察组的最大剂量(D_(1)、D_(2))、平均剂量(D_(mean))、靶区均匀性指数(HI)高于对照组,靶区处方剂量覆盖(D_(95))、接近最小剂量(D_(98))、适形度指数(CI)、治疗时间、治疗跳数低于对照组,膀胱D_(mean)、45 Gy辐射剂量体积百分比(V_(45))、40 Gy辐射剂量体积百分比(V_(40))、30 Gy辐射剂量体积百分比(V_(30))和股骨头V_(45)、V_(40)高于对照组,股骨头D_(mean)、V_(30)低于对照组,差异均具有统计学意义(P<0.05)。结论:在宫颈癌的放射治疗中,螺旋断层放疗具有明显的剂量学优势,且靶区适形度、剂量均匀性更优,容积旋转调强放疗所需治疗时间更短,治疗效率更优。在实际诊疗中,医师可根据患者具体病情、个体差异,选择适宜的放疗方式。

Objective To investigate the dosimetric differences and advantages between helical tomotherapy and volumetric rotary intensity-modulated radiotherapy for cervical cancer.Methods 20 patients with cervical cancer admitted to the First Affiliated Hospital of Bengbu Medical College from January 2021 to January 2022 were selected.All patients were treated with helical tomotherapy (data as the control group),and after 4 weeks of treatment,they were adjusted to volumetric rotary intensity modulated radiotherapy (data as the observation group).The dosimetric differences between the two radiotherapy methods were compared.Results The maximum dose (D_(1),D_(2)),average dose (D_(mean)) and target homogeneity index (HI) of the observation group were higher than those of the control group,and the prescription dose coverage (D_(95)),near minimum dose (D_(98)),conformal index (CI),treatment time and treatment hop number of the observation group were lower than those of the control group.The bladder D_(mean),45 Gy radiation dose volume percentage (V_(45)),40 Gy radiation dose volume percentage (V_(40)),30 Gy radiation dose volume percentage (V_(30)) and V_(45) and V_(40) of femoral head were higher than those of the control group,while the femoral head D_(mean) and V_(30) were lower than those of the control group,the differences were statistically significant (P < 0.05).Conclusion In the radiotherapy of cervical cancer,helical tomotherapy has obvious dosimetric advantages,and the target volume conformation and dose uniformity are better,the treatment time of volumetric rotary intensity modulated radiotherapy is shorter,and the treatment efficiency is better.In actual diagnosis and treatment,physicians can choose the appropriate radiotherapy method according to the patient’s specific condition and individual differences.