昆明地区妊娠期妇女、婴幼儿维生素D水平分析及妊娠期空腹血糖水平与维生素D水平的关联性

Analysis of Vitamin D Level in Pregnant Women and Infants in Kunming and Study on the Relationship between Fasting Blood Glucose Level and Vitamin D Level during Pregnancy

目的通过分析昆明地区妊娠期妇女和婴幼儿血清25羟维生素D(25OHD)群体水平,了解当地此类人群维生素D营养状况,同时探究维生素D与妊娠期糖尿病发生风险,为补充维生素D提供合理性建议。方法采集正常孕妇婴幼儿血清25OHD检测结果和血糖水平等数据,通过SPSS19.0进行数据分析。结果昆明地区妊娠期妇女与婴幼儿血清25OHD的3a整体水平为(20.41±8.08)ng/mL、(29.14±8.89)ng/mL、(31.67±9.77)ng/mL。2018年至2020年血清25OHD缺乏比例由7.31%减少至0.09%,不足比例由66.7%减少至7.95%。孕妇血清25OHD与其血糖水平存在负相关性。结论昆明地区妊娠期妇女与婴幼儿血清25OHD整体水平逐年上升,各年龄段的血清25OHD水平呈现出婴幼儿略高,维生素D水平一定程度上对血糖水平存在影响,孕妇适当补维生素D,以食物和适当光照为主,维生素D制剂为辅,不仅有利于防治缺钙等相关疾病,而且有助于稳定妊娠期妇女血糖水平。

Objective To understand the vitamin D nutritional status of pregnant women and infants in Kunming by analyzing the serum level of 25 hydroxyvitamin D(25OHD),and to explore the relationship between vitamin D and the risk of gestational diabetes so as to provide reasonable suggestions for vitamin D supplementation.Methods The serum 25OHD and blood glucose levels of normal pregnant women and infants were collected and analyzed by SPSS19.0.Results The overall levels of serum 25OHD in pregnant women and infants in Kunming were(20.41±8.08)ng/mL,(29.14±8.89)ng/mL and(31.67±9.77)ng/mL.From 2018 to 2020,the deficiency rate of serum 25OHD decreased from 7.31%to 0.09%,and the deficiency rate decreased from 66.7%to 7.95%.There was a negative correlation between serum 25OHD and blood glucose level in pregnant women.Conclusion The overall level of serum 25OHD in pregnant women and infants in Kunming has been increasing year by year,and the level of serum 25OHD in all ages shows a slightly higher level in infants.Vitamin D level has an impact on blood glucose level to some extent.Pregnant women should take vitamin D supplements,mainly with food and sunshine,appropriate light,supplemented by vitamin D preparation.It is not only beneficial to the prevention and treatment of which can not only prevent the calcium deficiency and other related diseases,but also helps to stabilize the blood sugar level of women during pregnancy.