基于超声容积成像定量评估甲状腺肿大源性气道压迫的风险研究

Quantitative Assessment of the Risk of Goiter-Derived Airway Compression Based on Ultrasound Volumetric Imaging

目的:评估甲状腺超声容积成像是否可以定量评估甲状腺肿大源性气道压迫的风险。方法:回顾性收集2017年1月至2020年12月期间实施过甲状腺超声容积成像和气道(颈部)CT成像的受试者资料84例。三维超声图像分析均采用Render表面模式。气道CT成像采用薄层成像辅助多平面重建(MPR)、曲面重建(CPR)及容积重建(VR)模式。结果:气道狭窄组和非狭窄组之间存在显著的甲状腺TV差异(t=13.363,P<0.001),且与气道狭窄程度呈显著相关性(r=0.549,P<0.05)。甲状腺体积对气道压迫发生的鉴别效能为0.679(95%可信区间:0.599~0.753,P<0.001),对气管狭窄10%、20%、30%和40%的鉴别效能分别为0.658、0.679、0.702、0.787,截断值19.69mL、20.98mL、23.85mL和29.37mL。结论:甲状腺超声成像能够准确的定量评估其引发的气道压迫风险,其可作为气道压迫防治方案的可靠理论依据。

Objective:To evaluate whether thyroid ultrasound volume imaging can quantitatively evaluate the risk of airway compression caused by goiter.Methods:The data of 84 subjects who underwent thyroid ultrasound volume imaging and airway(neck)CT imaging from January 2017 to December 2020 were collected retrospectively.The render surface mode was adopted in the three-dimensional ultrasonic image analysis.The thin layer imaging assisted multiplanar reconstruction(MPR),curved surface reconstruction(CPR),and volume reconstruction(VR)were used for airway CT imaging.Results:There was a significant difference in thyroid TV between the airway stenosis group and the non-stenosis group(t=13.363,P<0.001),and it was significantly correlated with the degree of airway stenosis(r=0.549,P<0.05).The differential efficacy of thyroid volume for airway compression was 0.679(95%CI:0.599-0.753,P<0.001),and the differential efficacy for tracheal stenosis was 0.658,0.679,0.702 and 0.787,respectively.The cut-off values were 19.69ml,20.98ml,23.85ml,and 29.37ml.Conclusion:Thyroid ultrasound imaging can accurately and quantitatively evaluate the risk of airway compression,which can be used as a reliable theoretical basis for the prevention and treatment of airway compression.