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伴狼疮样表现的IgG4相关疾病

A case of IgG4 related disease with SLE-like manifestations
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摘要 64岁男性,以皮疹、多处淋巴结肿大起病,尿液检查提示少量蛋白尿,无明显镜下血尿,血清肌酐升高,溶血性贫血,抗核抗体、抗双链DNA抗体阳性,补体下降,血清IgG4水平升高,肾活检病理提示IgG4相关间质性肾炎。结合临床及病理最终诊断伴狼疮样表现的IgG4相关疾病。 The patient was a male aged 64 year old with the following symptoms:rash and multiple enlarged lymph nodes.Laboratory examination results showed proteinuria,renal dysfunction,hemolytic anemia,antinuclear antibodies(ANAs)positivity,anti-dsDNA antibodies(AdsDNA)positivity,hypocomplementemia,and elevated serum IgG4 levels.Renal biopsy showed IgG4-positive-plasma cell infiltration in renal interstitium.Based on the clinical and pathological manifestations,the patient was final diagnosed as IgG4 related disease with SLE-like manifestations.
作者 金英 赵丽丽 焦晨峰 梁少姗 程震 JIN Ying;ZHAO Lili;JIAO Chenfeng;LIANG Shaoshan;CHENG Zhen(National Clinical Research Center of Kidney Diseases,Jinling Hospital,Nanjing University School of Medicine,Nanjing 210016,China)
出处 《肾脏病与透析肾移植杂志》 CAS CSCD 北大核心 2022年第4期395-400,共6页 Chinese Journal of Nephrology,Dialysis & Transplantation
关键词 溶血性贫血 IgG4相关疾病 系统性红斑狼疮 hemolytic anemia IgG4-related disease systemic lupus erythematosus
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