多学科药师团队对普外科复杂消化道手术患者分级药学监护的效果评价

Effect Evaluation of Graded Pharmaceutical Care Carried on Patients with Complex Digestive Tract Surgery in the General Surgery Department by Multi-disciplinary Pharmacist Teams

目的通过成立多学科药师团队,开展分级药学监护,探索临床药师实施药学监护的创新模式拟在不同专科的临床药师中推广。方法将175例患者分为观察组82例和对照组93例。2020年1—9月纳入患者为对照组,由单一临床药师实施药学监护,不规定药学监护级别和频次。2020年10月—2021年5月纳入患者为观察组,由多学科药师团队实施分级药学监护。比较两组患者的药物治疗效果与合理用药指标。结果观察组抗感染治疗有效率(94.74%)高于对照组(86.21%)、出院时前白蛋白水平(26.35±7.61)g·L^(-1)高于对照组(20.61±5.27)g·L^(-1)、疼痛控制率(87.80%)高于对照组(74.19%);观察组患者的药物治疗费用(24019.30±1440.62)元低于对照组(25764.90±1299.54)元,抗菌药物使用强度[45.10 DDDs/(100人·天)]低于对照组[52.24 DDDs/(100人·天)],上述指标均差异有统计学意义(P<0.05)。结论由多学科药师团队实施分级药学监护,可以改善患者的治疗结局,优化治疗费用支出结构,为临床药师进行药学监护提供了参考模式。

Objective Through the establishment of a multidisciplinary pharmacist team,graded pharmaceutical care is carried out,and an innovative model of clinical pharmacists implementing pharmacy monitoring is explored to promote pharmaceutical care among clinical pharmacists of different specialties.Methods A total of 175 patients were divided into an observation group(n=82)and a control group(n=93).Patients enrolled from January to September 2020 were included in the control group,in which a single clinical pharmacist performed pharmaceutical care without specifying the level and frequency of the pharmaceutical care.Patients enrolled from October 2020 to May 2021 were included in the observation group,in which a multi-disciplinary pharmacist team implemented graded pharmaceutical care.The therapeutic effect and rational drug use index between two groups were then compared.Results The effective rate of anti-infective treatment in the observation group(94.74%)was higher than that in the control group(86.21%),and the pre-albumin level at discharge[(26.35±7.61)g·L^(-1)]was higher than that in the control group[(20.61±5.27)g·L^(-1)],and the pain control rate(87.80%)was higher than that in the control group(74.19%).The cost of drug treatment in the observation group[(24019.30±1440.62)CNY]was lower than that in the control group[(25764.90±1299.54)CNY],and the antibiotics use intensity[45.10 DDDs/(100 person·days)]was lower than that in the control group[52.24 DDDs/(100 person·days)].Conclusion The graded pharmaceutical care implemented by a multi-disciplinary pharmacist team can improve the treatment outcomes and optimize the expenditure structure of treatment costs.The innovative establishment of the graded pharmaceutical care model provides a reference for the standardized pharmaceutical care.