益气化痰活血法治疗急性冠状动脉综合征的临床疗效观察

Clinical Observation on the Treatment of Acute Coronary Syndrome by Supplementing Qi,Removing Phlegm and Activating Blood

目的 观察不同用药方案用于治疗急性冠状动脉综合征(ACS)患者临床治疗中的效果,探究药物作用机制。方法 选择2018年5月至2019年5月入住我院的46例ACS病患,随机分为传统组、试验组,均予以西药治疗,试验组联合益气化痰活血中药汤。治疗14 d后,观察各组患者中医证候疗效、血脂水平及不良反应发生情况。结果 试验组中医证候总有效率为95.65%,高于传统组的73.91%(P <0.05);治疗后,两组患者血脂(TC、TG、LDL-C与HDL-C)和治疗前相比均有改善,试验组改善程度比传统组更为显著(P <0.05);传统组不良反应发生率为17.39%,试验组为13.04%%,无统计学意义(P> 0.05)。结论 在予以ACS患者使用益气化痰活血中药汤,和单纯西药物治疗相比,能更有效的改善病况,而且过程相对较安全,值得推广。

Objective To observe the clinical effects of different drug regimens in the treatment of patients with acute coronary syndrome(ACS) and explore the mechanism of drug action. Methods Forty-six patients with ACS who were admitted to our hospital from May 2018 to May 2019were randomly divided into the traditional group and the experimental group. They were all treated with western medicine. The experimental group was combined with traditional Chinese medicine decoction to supplementing qi, removing phlegm and activating blood circulation. After 14 days of treatment, the efficacy of TCM syndromes, blood lipid levels and adverse reactions in each group were observed. Results The total effective rate of TCM syndrome in the experimental group was 95.65%, higher than 73.91% in the traditional group(P<0.05). After treatment, the blood lipid of the two groups(TC, TG, LDL-C and HDL-C) was improved compared with that before treatment, and the improvement degree of the experimental group was more significant than that of the traditional group(P<0.05). The incidence of adverse reactions was 17.39% in the traditional group and 13.04% in the experimental group, showing no statistical significance(P>0.05). Conclusion Compared with western medicine alone, the traditional Chinese medicine decoction for supplementing qi, removing phlegm and activating blood circulation in ACS patients can improve the condition more effectively, and the process is relatively safe, which is worthy of promotion.