处方复杂度量表的汉化改良与在老年糖尿病患者中的信效度检验

Development of the modified medication regimen complexity index of Chinese version(mMRCI-C) and its validation in elderly diabetic patients

目的翻译并改良英文版处方复杂度(MRCI)量表,形成改良版处方复杂度中文(mMRCI-C)量表并对其进行信效度检验。方法取得翻译英文版MRCI量表授权后,按照Brislin翻译模型对英文版MRCI量表进行翻译与回译,通过2轮专家函询和预调查对mMRCI-C量表初稿进行文化调试,针对语义、内容和概念对等性等方面进行修改,确定mMRCI-C量表内容。于2020年10—11月在上海市长风社区卫生服务中心糖尿病专病门诊,对就诊的420例≥60岁糖尿病患者,进行一般资料调查和mMRCI-C量表的信、效度验证。mMRCI-C量表的信度采用重测信度和内部一致性信度进行检验,效度采用内容效度、聚合效度与区分效度进行检验。结果mMRCI-C量表包括3个维度,分别为药物剂型(14个条目)、用药频率(5个条目)、用药说明(6个条目),共25个条目。共发放问卷430份,回收有效问卷420份。问卷应答者中男性212例(50.4%),女性208例(49.6%),平均年龄(71.4±8.1)岁。量表的重测信度为0.999,内部一致性信度为0.849;内容效度均>0.80,聚集效度r=0.932,区分效度P<0.001。结论经初步验证,mMRCI-C量表信、效度良好。

Objective To develop the modified medication regimen complexity index of Chinese version(mMRCI-C)and test its reliability and validity.Method The Chinese version of MRCI was developed by modification,translation and back translation.The MRCI was interculturally adapted by 2-rounds of expert consultation and pilot study to ensure the semantics,content and conceptual equivalence.The validation of the mMRCI-C scale was tested among 420 community-dwelling elderly patients with type 2 diabetes mellitus(T2DM)in Shanghai Changfeng Community Health Service Center from October to December 2020.SPSS 23.0 was used to analyze the reliability and validity of the scale.Results The mMRCI-C scale included 3 dimensions,namely drug dosage form(14 entries),medication frequency(5 entries),and additional instructions(6 entries),with a total of 25 entries.Among 420 valid questionnaires collected,the respondents were 212 males(50.4%)and 208 females(49.6%)with a mean age of(71.4±8.1)years.The test-retest reliability was 0.999 and internal consistency reliability was 0.849.The content validity exceeded 0.80,the convergent validity was 0.932;and discriminant validity P<0.001.Conclusion The preliminary testing results show that the reliability and validity of the mMRCI-C scale are satisfactory.