儿童急性淋巴细胞白血病长期生存的康复管理

Long-term Rehabilitation Management of Childhood Acute Lymphoblastic Leukemia Survivors

急性淋巴细胞白血病占儿童白血病的75%~85%,随着诊疗技术的进步,我国儿童ALL长期无事件生存率达70%~80%。因此,ALL患儿远期躯体功能状态和生活质量越来越受到重视。尽管近20年来肿瘤康复在欧美国家发展迅速,但儿童白血病康复的临床干预措施和学术研究方面仍存在诸多不足,我国儿童白血病康复工作更是落后于西方发达国家。本文中,我们描述了一个相对全面的儿童急性淋巴细胞白血病长期生存康复管理框架,以期更好地提高ALL患儿的远期生存质量。

Acute lymphoblastic leukemia(ALL)accounts for 75%-85% of the cases of childhood leukemia.As a result of the progress made in diagnosis and treatment,an event-free survival rate of 70%–80% has been reported in our country.Consequently,research should focus on long-term physical function and quality of life of childhood ALL survivors.In the past 20 years,cancer rehabilitation has achieved rapid development in European and American countries,but gaps remain in clinical practice and academic research of rehabilitation for childhood leukemia.Specifically,rehabilitation for childhood leukemia in our country lags behind,compared with that in Western developed countries.In this commentary,we describe a relatively comprehensive childhood ALL survivorship care quality framework to improve patients’long-term quality of life.