1990年和2019年中国心血管疾病负担及危险因素研究

Disease Burden and Risk Factors of Cardiovascular Diseases in China in 1990 and 2019

目的:分析1990年和2019年中国心血管发病、死亡和疾病负担情况。方法:利用2019年全球疾病负担数据库,分析总人群、不同年龄组间1990年和2019年我国心血管发病、死亡、伤残调整寿命年(DALY)、过早死亡损失寿命年(YLL)和伤残损失寿命年(YLD)。并对心血管进行危险因素归因分析。结果:2019年中国心血管发病人数为1234.1万,发病率为867.65/10万,较1990年分别增长了132.82%和93.75%。2019年死亡人数458.43万,死亡率为322.30/10万,较1990年分别上升了89.12%和57.39%。2019年中国心血管DALY、YLD和YLL分别为9193.31万人年、1038.39万人年和8154.93万人年。较1990年分别上升了50.07%、146.82%和45.48%。2019年发病率、死亡率和DALY率最高的年龄组均为>70年龄组,分别为4646.78/10万、3057.82/10万和52696.68/10万。中国心血管归因于代谢危险导致的死亡人数、DALY和YLL最多,分别为3272924人、67112754人年和59934426人年。结论:我国心血管的疾病负担在1990-2019年间有较大增长,应采取积极的预防措施以减轻心血管的疾病负担。

Objective: To analyze the incidence, mortality and disease burden of cardiovascular diseases in China in 1990 and 2019. Methods: The global Burden of Disease database 2019 was used to analyze the cardiovascular incidence, mortality, disability-adjusted life years(DALY), years of life lost(YLL) and years lived with disability(YLD) in China between 1990 and 2019. Cardiovascular risk factor attribution analysis was performed. Results: In 2019, the number of cardiovascular diseases in China was 12.341 million, with the incidence of 867.65/100,000, an increase of 132.82% and 93.75% compared with 1990, respectively. In 2019, 4.5843 million people died, with a mortality rate of 322.30/100,000, up 89.12% and 57.39% respectively from 1990. In 2019, the cardiovascular DALY, YLD and YLL in China were 91,933,100, 10,383,900 person-years and 81,543,300 person-years, respectively. Compared with 1990, it increased by 50.07%, 146.82% and 45.48% respectively. In 2019, the age groups with the highest incidence, mortality and DALY rates were all > 70 age group, which were 4646.78/100,000, 3057.82/100,000 and 52696.68/100,000, respectively. The number of cardiovascular deaths due to metabolic risk, DALY and YLL were the highest in China, with 3,272,924, 6,711,2754 person-years and 5,993,426 person-years, respectively. Conclusion: The burden of cardiovascular diseases in China increased significantly from 1990 to 2019. Active preventive measures should be taken to reduce the burden of cardiovascular diseases.