基于艾考糊精透析液的腹膜透析治疗进展

Progress in peritoneal dialysis treatment based on icodextrin

艾考糊精通过其类似“胶体”渗透压的机制,应用于腹膜透析的长保留阶段并形成有效的超滤。在经典的基于艾考糊精透析液的治疗方案基础上,出现了每日单次使用艾考糊精透析液、每日2次使用艾考糊精透析液、艾考糊精与葡萄糖腹膜透析液联合等多种治疗方案,适用于不同的临床状况中。艾考糊精腹膜透析液的应用,有助于控制慢性心力衰竭,改善或维持心室结构。应用基于艾考糊精透析液的治疗方案将会有效地提升我国腹膜透析治疗的水平。

Icodextrin through a mechanism resembling‘colloid’osmosis forms effective ultrafiltration during the long dwelling phase of peritoneal dialysate.On the basis of the classic icodextrin dialysate-based treatment regimen,a variety of treatment schedules suitable for different clinical conditions have been developed,such as single daily use of icodextrin dialysate,twice daily use of icodextrin dialysate,and icodextrin combined with glucose peritoneal dialysate.Icodextrin dialysate can help control chronic heart failure and improve or maintain ventricular structure.The treatment regimen based on icodextrin dialysate will effectively improve our peritoneal dialysis treatment.