左布比卡因腰硬联合麻醉对老年下肢骨折的有效性及安全性分析

Effectiveness and Safety Analysis of Levobupivacaine Combined Spinal-epidural Anesthesia for Elderly Patients with Lower Limb Fractures

目的:探讨左布比卡因腰-硬联合麻醉对老年下肢骨折患者中的效果。方法:选取2017年5月—2019年5月我院收治并拟行手术治疗的老年下肢骨折患者86例,采用计算机产生随机序列将患者分为对照组和观察组,每组43例。对照组应用常规腰麻,观察组采取小剂量轻比重腰麻-硬麻醉,比较两组麻醉前及麻醉后5~20 min内各个时间点生命体征情况及不良反应发生情况。结果:两组麻醉前及麻醉后5~20min内各个时间点的SBP、DBP、HR比较,差异无统计学意义(P>0.05)。观察组术后头痛、恶心、认知功能障碍以及过敏反应发生率低于对照组,差异有统计学意义(P<0.05)。结论:左布比卡因小剂量-低比重腰-硬联合麻醉对老年患者效果较好,可降低不良反应发生概率,具有应用有效性及安全性。

Objective:To investigate the value of low-dose light specific gravity combined spinal epidural anesthesia with levobupivacaine in elderly patients and its effect on cognitive function.Methods:A total of 86 elderly patients with lower limb fractures who were treated in our hospital from May 2017 to May 2019 and scheduled for surgical treatment were selected and randomly divided into the control group and the observation group with 43 cases in each group.The control group was given routine spinal anesthesia,and the observation group was given low-dose and light-weight spinal anesthesiahard anesthesia.The vital signs and adverse reactions were compared between the two groups before anesthesia and 5-20 min after anesthesia.Results:There was no significant difference in SBP,DBP and HR between the two groups before anesthesia and within 5-20 min after anesthesia(P>0.05).The incidence of postoperative headache,nausea,cognitive dysfunction and allergic reactions in the observation group was lower than that in the control group,and the difference was statistically significant(P<0.05).Conclusion:Low-dose levobupivacaine-light-weight specific gravity combined spinal-epidural anesthesia has good effect on elderly patients,which can reduce the incidence of adverse reactions,and has application effectiveness and safety.