围术期神经认知障碍的研究进展

Research Progress of Perioperative Neurocognitive Disorders

围术期神经认知障碍是老年患者常见的围手术期并发症,其发病率较高,持续时间长短不一,症状可轻可重,严重者会出现永久性认知功能损伤,进一步发展为老年性痴呆。本文就PND的诊断、危险因素、发病机制、防治措施的最新研究予以综述,为更进一步的研究和临床工作指导提供新的视角。

Perioperative neurocognitive impairment is a common perioperative complication in elderly patients,which has a high incidence and duration,and the symptoms can be mild or severe.In severe cases,permanent cognitive impairment will occur and further develop into senile dementia.This article reviews the latest research on the diagnosis,risk factors,pathogenesis,prevention and treatment of PND,and provides a new perspective for further research and clinical work guidance.