罗伊适应模式干预对多发性骨髓瘤化疗患者依从性及癌因性疲乏的影响

Effect of Roy’s adaptation model intervention on compliance and cancer-related fatigue of multiple myeloma patients undergoing chemotherapy

目的探究罗伊适应模式干预对多发性骨髓瘤化疗患者依从性及癌因性疲乏的影响。方法将104例多发性骨髓瘤患者按照随机数字表法分为观察组和对照组,每组52例。对照组患者接受常规护理干预,观察组患者接受罗伊适应模式干预。比较两组患者的负性情绪、化疗依从性、癌因性疲乏情况以及生活质量。结果干预后,两组患者抑郁自评量表(SDS)和焦虑自评量表(SAS)评分均低于本组干预前,且观察组患者SDS和SAS评分均低于对照组,差异均有统计学意义(P﹤0.05)。观察组患者化疗依从率、癌因性疲乏情况均优于对照组,差异均有统计学意义(P﹤0.05)。干预后,两组患者健康调查简表(SF-36)各维度评分均高于本组干预前,且观察组患者SF-36各维度评分均高于对照组,差异均有统计学意义(P﹤0.05)。结论罗伊适应模式干预应用于多发性骨髓瘤的化疗,能够改善患者的负性情绪和癌因性疲乏情况,提高患者的化疗依从率和生活质量。

Objective To explore the effect of Roy’s adaptation model intervention on compliance and cancer-related fatigue of multiple myeloma patients undergoing chemotherapy.Method A total of 104 multiple myeloma patients were divided into observation group(n=52,received Roy’s adaptation model intervention)and control group(n=52,received routine nursing intervention)according to the random number table.The negative emotion,chemotherapy compliance,cancer-related fatigue and quality of life in the two groups were compared.Result After intervention,the scores of selfrating depression scale(SDS)and self-rating anxiety scale(SAS)in both groups were lower than those before intervention,with lower scores in the observation group than those in the control group(P<0.05).The compliance rate of chemotherapy and cancer-related fatigue in observation group were better than those in the control group(P<0.05).The scores of the MOS 36-item short form health survey(SF-36)in both groups were higher than those before intervention,with higher scores in the observation group than those in the control group(P<0.05).Conclusion Roy’s adaptation model intervention in chemotherapy of multiple myeloma can improve patients’negative emotion and cancer-related fatigue,and improve patients’chemotherapy compliance rate and quality of life.