郑氏排痰阀联合常规治疗对支气管扩张伴感染患者临床疗效及呼吸道顺应性和胸部CT影像的影响

Effects of Zheng's expectoration valve combined with conventional treatment on clinical efficacy,respiratory compliance and chest CT images in patients with bronchiectasis complicated by infection

目的探讨郑氏排痰阀联合常规治疗对支气管扩张伴感染患者临床疗效及呼吸道顺应性和胸部CT影像的影响。方法选取2020年1月至2021年3月本院收治的88例支气管扩张伴感染患者作为研究对象,按照随机数字表法分为两组,各44例。对照组给予常规治疗,观察组在对照组基础上联合郑氏排痰阀治疗,比较两组临床疗效、治疗前后呼吸道顺应性及胸部CT影像表现。结果观察组治疗总有效率为95.45%,高于对照组的77.27%,差异有统计学意义(P<0.05)。治疗后,观察组用力肺活量(FVC)、第1秒用力呼气容积(FEV1)、肺活量75%时用力呼气流速(Vmax75%)、用力肺活量的25%~75%呼气中期流速(FEE 25%~75%)均高于对照组,差异有统计学意义(P<0.05)。治疗后,观察组支气管内径/伴行肺动脉直径>1、从中心到外周支气管未逐渐变细、距外周胸膜1 cm或接近纵膈膜范围内可见支气管影、影像表现占比均低于对照组,无病变影像表现占比高于对照组,差异有统计学意义(P<0.05)。结论郑氏排痰阀联合临床常规治疗支气管扩张伴感染效果显著,可改善患者的呼吸道顺应性,减轻其肺部病变程度。

Objective To investigate the effects of Zheng's expectoration valve combined with conventional treatment on the clinical efficacy,respiratory compliance and chest CT images of patients with bronchiectasis complicated by infection.Methods 88 patients with bronchiectasis complicated by infection in our hospital from January 2020 to March 2021 were selected as the study subjects,and they were divided into two groups according to random number table method,with 44 cases in each group.The control group was given conventional treatment,and the observation group was treated with Zheng's expectoration valve treatment on the basis of the control group.The clinical efficacy,respiratory compliance and chest CT images before and after treatment were compared between the two groups.Results The total effective rate of the observation group was 95.45%,which was higher than 77.27%of the control group,and the difference was statistically significant(P<0.05).After treatment,forced vital capacity(FVC),forced expiratory volume in one second(FEV1),maximal expiratory flow rate at 75%forced vital capacity(Vmax75%)and mid-expiratory flow rate at 25%-75%of forced vital capacity(FEE 25%-75%)in the observation group were higher than those in the control group,and the differences were statistically significant(P<0.05).After treatment,the ratio of bronchial diameter/associated pulmonary artery diameter>1,bronchial shadow within 1 cm from the peripheral pleura or close to the mediastinum and imaging manifestations in the observation group were lower than those in the control group,and the ratio of imaging manifestations without lesions was higher than that in the control group,and the differences were statistically significant(P<0.05).Conclusion Zheng's expectoration valve combined with clinical routine treatment of bronchiectasis with infection has significant effect,which can improve the respiratory compliance of patients,and reduce the degree of pulmonary lesions.