溃疡性结肠炎患者1年内复发的影响因素

Influencing factors of recurrence in patients with ulcerative colitis within 1 year

目的调查分析溃疡性结肠炎(ulcerative colitis,UC)患者1年内复发的影响因素。方法选择2018年1月—2019年6月医院收治的120例溃疡性结肠炎患者的为研究对象,将出院后1年内复发的患者纳入复发组(病例组),1年内未复发的患者作为对照组,采用用药依从性问卷、疾病认知度问卷、家庭关怀度问卷、症状自评量表等对患者进行调查,通过单因素和多因素Logistic回归分析影响患者疾病复发的相关因素。结果120例UC患者中,有32例1年内未复发;单因素分析显示,患者病情严重程度、长期吸烟史、酗酒史、饮食喜好、用药依从性、家庭关怀度、疾病认知度和SCL-90评分与UC复发存在相关性(P<0.05);多因素Logistic回归分析显示,患者病情严重程度、饮食习惯、用药依从性、疾病认知度、家庭关怀度和SCL-90评分均是UC复发的独立性影响因素(P<0.05)。结论UC疾病复发率高,复发与患者病情、不良饮食习惯、家庭关怀度、心理状况等因素密切相关,临床中应针对危险因素对患者进行及时有效的预防护理和健康指导,以减少复发。

Objective To investigate and analyze the infl uencing factors of recurrence in patients with ulcerative colitis(UC)within 1 year.Methods A total of 120 patients with ulcerative colitis admitted in the hospital from January 2018 to June 2019 were selected as the research objects.Patients with recurrence within 1 year after discharge were involved in the recurrence group(case group),patients without recurrence within 1 year were involved in the control group.Medication compliance questionnaire,disease awareness questionnaire,family care questionnaire and symptom self-rating scale were used to investigate the patients.Univariate and multivariate Logistic regression analysis was used to analyze the related factors affecting the patients'disease recurrence.Results Among 120 UC patients,32 had no recurrence within 1 year.Univariate analysis showed that the severity of disease,long-term smoking history,drunk history,diet preference,medication compliance,family care,disease awareness and SCL-90 score were correlated with UC recurrence(P<0.05).Multivariate Logistic regression analysis showed that the severity of the disease,dietary habits,medication compliance,disease awareness,family care and SCL-90 score were independent infl uencing factors of UC recurrence(P<0.05).Conclusion The recurrence rate of UC disease was high,and the recurrence was closely related to the patient's condition,poor eating habits,family care,psychological status and other factors.In clinical practice,timely and eff ective preventive nursing and health guidance should be given to patients according to the risk factors to reduce the recurrence rate.