全球猴痘病毒知识图谱和多维主题分析研究

Knowledge Map and Multidimensional Analysis of Monkeypox Virus Research

2022年5月以来,非洲以及多个非流行国家相继报告猴痘确诊病例,三个多月已造成全球90余个国家超4万例病例,世界卫生组织已于2022年7月23日宣布此次猴痘疫情为“国际关注的突发公共卫生事件”。本文基于文献计量学方法对1962-2022年间国际猴痘病毒领域的研究论文进行了多维分析,对猴痘病毒领域的整体研究态势和研究主题进行了知识图谱呈现,以期为相关领域研究提供情报参考。结果表明,猴痘病毒研究领域可大体分为初始发展期、快速增长期、集中暴发期和徘徊持续期,美国在该研究领域具有独强优势,猴痘病毒的流行病学、分子遗传和致病机理、疫苗制备和药物研发是主要的研究主题。研究分析,我国在猴痘病毒遗传机制和致病机理、猴痘疫苗和药物研发、猴痘病毒病原学和相关新生物技术方法等领域的布局和研究需加强,猴痘病毒相关基础研究和应用技术储备值得相关科技机构和科研群体关注及提供科学依据。

From early May to the end of June 2022,confirmed cases of monkeypox have been reported in Africa and many non-epidemic countries-in just 3 months,there have been>40,000 cases in>90 countries.On July 23,the World Health Organization announced that the monkeypox epidemic is a“public health emergency of international concern”.Using bibliometric methods,this paper presents a multidimensional analysis of international research papers in the field of monkeypox virus research from 1962 to 2022,and a knowledge map of the overall research situation and research topics in the monkeypox virus field.The results show that research into monkeypox virus can be roughly divided into an initial development period,rapid growth period,concentrated outbreak period,and wandering duration period.The USA has a unique advantage in this research field.Epidemiology,molecular genetics,pathogenesis,vaccine preparation,and drug development have been the main research topics.Our findings show that research into monkeypox virus,and development of understanding of the genetic and pathogenic mechanisms,vaccines and drugs,etiology,and viral-related biotechnology methods,need to be strengthened in China.Relevant basic research and applied technology reserves should attract the attention of scientific and technological administrative departments and scientific research groups.