腰痛宁胶囊结合康复训练在腰椎间盘突出症治疗中的应用研究

Application of Yaotongning Capsules Combined with Rehabilitation Training in the Treatment of Lumbar Disc Herniation

目的:探讨腰痛宁胶囊结合康复训练在腰椎间盘突出症(LDH)治疗中的应用效果。方法:选取2018年10月至2020年10月武汉市江夏区第一人民医院收治的LDH患者84例,按照随机数字表法分为观察组(42例)和对照组(42例),观察组患者给予口服腰痛宁胶囊+康复训练,对照组患者给予口服腰痛宁胶囊。观察两组患者的治疗效果,比较两组患者治疗前后的中医证候积分、腰背疼痛程度、腰椎功能及不良反应。结果:与治疗前比较,两组患者治疗后的中医证候积分及疼痛视觉模拟评分(VAS)均降低,日本骨科协会评估治疗评分(JOA)均升高,差异均有统计学意义(P<0.05);与对照组比较,观察组患者治疗后的中医证候积分及VAS评分更低,JOA评分更高,差异均有统计学意义(P<0.05)。观察组患者的治愈显效率、临床总有效率分别为73.81%(31/42)、95.24%(40/42),明显高于对照组的52.38%(22/42)、80.95%(34/42),差异均有统计学意义(P<0.05)。两组患者的不良反应主要为轻度胃腹胀痛、皮疹、头晕和恶心呕吐等,两组患者总不良反应发生率的差异无统计学意义(P>0.05)。结论:腰痛宁胶囊结合康复训练治疗LDH安全有效,利于患者疼痛症状的缓解及腰椎功能的改善。

OBJECTIVE:To probe into the application of Yaotongning capsules combined with rehabilitation training in the treatment of lumbar disc herniation(LDH).METHODS:A total of 84 patients with LDH admitted into Wuhan Jiangxia District the First People’s Hospital from Oct.2018 to Oct.2020 were extracted to be divided into the observation group(n=42)and the control group(n=42)via the random number table method.The observation group was given oral Yaotongning capsules and rehabilitation training,while the control group received oral Yaotongning capsules.The therapeutic effects of two groups were observed,and traditional Chinese medicine symptom scores,degree of low back pain,lumbar spine function before and after treatment and adverse drug reactions were compared between two groups.RESULTS:Compared before treatment,the traditional Chinese medicine syndrome scores and pain visual analogue scale(VAS)scores of two groups after treatment decreased,and the Japanese Orthopaedic Association(JOA)assessment and treatment score increased,the differences were statistically significant(P<0.05).Compared with the control group,the traditional Chinese medicine syndrome score and VAS score of the observation group after treatment were lower,and the JOA score was higher,the differences were statistically significant(P<0.05).The cure rate and clinical total effective rate of the observation group were respectively 73.81%(31/42)and 95.24%(40/42),significantly higher than 52.38%(22/42)and 80.95%(34/42)of the control group,with statistically significant differences(P<0.05).The main adverse drug reactions of two groups were mild stomach distension and pain,rash,dizziness,nausea and vomiting,etc.There was no statistically significant difference in the incidence of total adverse drug reactions between two groups(P>0.05).CONCLUSIONS:Yaotongning capsule combined with rehabilitation training is safe and effective in the treatment of LDH,which is conducive to the relief of pain symptoms and the improvement of lumbar spine function.